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During a mean follow-up of 3.4 years,stroke occurred at an annual rate of 8.5%among patients and 0.8%among controls(adjusted relative risk,9.9;95% CI,2.3 to 43.1;P=0.002).Nineteen strokes occurred,17 in patients and 2 in controls;all were nonfatal cerebral infarctions.Twelve of the 17 that occurred in patients were in a carotid artery territory ipsilateral to the qualifying retinal cholesterol embolus and 5 were in another vascular territory.Ocular infarction or hemorrhagic stroke did not occur.Nonfatal myocardial infarction or vascular death occurred at an annual rate of 7.7% among patients and 4.9%among controls(adjusted relative risk,1.4;95%CI,0.7 to 2.9;P=0.39).Asymptomatic retinal cholesterol embolism is an important risk factor for cerebral infarction independent of commonly recognized vascular risk factors. |
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carotid artery disease
cerebral infarction
cerebrovascular accident
cerebrovascular disease,risk factors in
embolism,cholesterol
embolism,retinal
endarterectomy,carotid
Hollenhorst plaque
prognosis
risk factors
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